Calendario Pittsburgh Pirates - 2021
| FECHA | OPONENTE | Resultado | G-P | WIN | PERDIDO | SALVADO | ASIS |
| Vie., 16 de Jul. | G4-1 | 35-56 | Kuhl 3-5 | Stroman 6-8 | Rodriguez 13 | 18,119 | |
| Sáb., 17 de Jul. | G9-7 | 36-56 | Holmes 3-2 | Diaz 3-4 | 27,222 | ||
| Dom., 18 de Jul. | P7-6 | 36-57 | Familia 6-1 | Rodriguez 4-2 | May 2 | 17,837 | |
| Lun., 19 de Jul. | P4-2 | 36-58 | Smith 3-6 | De Jong 1-4 | Soria 5 | 9,173 | |
| Mar., 20 de Jul. | P11-6 | 36-59 | Bukauskas 2-2 | Davis 0-1 | 7,283 | ||
| Mié., 21 de Jul. | P6-4 | 36-60 | de Geus 2-0 | Underwood Jr. 2-3 | Soria 6 | 7,863 | |
| Vie., 23 de Jul. | G6-4 | 37-60 | Stratton 3-0 | Leone 2-1 | Rodriguez 14 | 26,579 | |
| Sáb., 24 de Jul. | G10-2 | 38-60 | Crowe 2-5 | Gausman 9-4 | 30,780 | ||
| Dom., 25 de Jul. | P6-1 | 38-61 | Wood 9-3 | Brubaker 4-10 | 30,303 | ||
| Mar., 27 de Jul. | P9-0 | 38-62 | Anderson 3-5 | Oviedo 1-2 | 10,618 | ||
| Mié., 28 de Jul. | P7-3 | 38-63 | Houser 7-5 | Kranick 1-2 | 10,204 | ||
| Jue., 29 de Jul. | P12-0 | 38-64 | Peralta 8-3 | Kuhl 3-6 | 10,503 | ||
| Vie., 30 de Jul. | G7-0 | 39-64 | Crowe 3-5 | Velasquez 3-6 | 20,591 | ||
| Sáb., 31 de Jul. | G3-2 | 40-64 | Stratton 4-0 | Alvarado 6-1 | 32,071 | ||
| Dom., 1 de Ago. | P15-4 | 40-65 | Gibson 7-3 | Keller 3-8 | 17,875 | ||
| Lun., 2 de Ago. | P6-2 | 40-66 | Lauer 4-4 | Wilson 2-4 | Boxberger 4 | 23,563 | |
| Mar., 3 de Ago. | G8-5 F/10 | 41-66 | Bednar 3-1 | Hardy 0-1 | 24,902 | ||
| Mié., 4 de Ago. | P4-2 | 41-67 | Suter 10-5 | Keller 0-1 | Williams 1 | 28,003 | |
| Jue., 5 de Ago. | P7-4 | 41-68 | Gray 4-6 | Crowe 3-6 | Givens 1 | 19,393 | |
| Vie., 6 de Ago. | P10-0 | 41-69 | Miley 9-4 | Brubaker 4-11 | 27,804 | ||
| Sáb., 7 de Ago. | P11-3 | 41-70 | Gutierrez 7-3 | Keller 3-9 | 31,297 | ||
| Dom., 8 de Ago. | P3-2 | 41-71 | Mahle 9-3 | Wilson 2-5 | Givens 2 | 23,740 | |
| Mar., 10 de Ago. | P4-1 | 41-72 | Happ 6-6 | Brault 0-1 | Reyes 26 | 10,056 | |
| Mié., 11 de Ago. | P4-0 | 41-73 | Wainwright 11-6 | Crowe 3-7 | 8,548 | ||
| Jue., 12 de Ago. | P7-6 | 41-74 | McFarland 2-0 | Brubaker 4-12 | Reyes 27 | 8,676 | |
| Vie., 13 de Ago. | Pospuesto | ||||||
| Sáb., 14 de Ago. | G14-4 F/7 | 42-74 | Shreve 1-0 | Anderson 4-6 | 16,991 | ||
| Sáb., 14 de Ago. | P6-0 F/7 | 42-75 | Boxberger 5-3 | Keller 3-10 | 24,081 | ||
| Dom., 15 de Ago. | P2-1 | 42-76 | Suter 12-5 | Peters 0-1 | Hader 23 | 12,001 | |
| Lun., 16 de Ago. | P2-1 | 42-77 | Treinen 3-5 | Shreve 1-1 | Jansen 24 | 48,005 | |
| Mar., 17 de Ago. | P4-3 | 42-78 | Knebel 2-0 | Ponce 0-3 | Jansen 25 | 53,114 | |
| Mié., 18 de Ago. | P9-0 | 42-79 | White 1-1 | Brubaker 4-13 | 52,140 | ||
| Vie., 20 de Ago. | G4-0 | 43-79 | Keller 4-10 | Mikolas 0-1 | 28,406 | ||
| Sáb., 21 de Ago. | G5-4 | 44-79 | Shreve 2-1 | Cabrera 2-4 | Bednar 1 | 30,205 | |
| Dom., 22 de Ago. | P3-0 | 44-80 | Wainwright 12-7 | Brault 0-2 | Reyes 28 | 34,431 | |
| Lun., 23 de Ago. | G6-5 | 45-80 | Banda 2-0 | Ramirez 0-1 | Bednar 2 | 8,596 | |
| Mar., 24 de Ago. | G4-2 | 46-80 | Brubaker 5-13 | Bumgarner 7-8 | Stratton 2 | 8,478 | |
| Mié., 25 de Ago. | P5-2 | 46-81 | de Geus 3-2 | Banda 2-1 | Clippard 5 | 8,357 | |
| Jue., 26 de Ago. | G11-7 | 47-81 | Kuhl 4-6 | Cabrera 2-5 | 8,618 | ||
| Vie., 27 de Ago. | P4-3 | 47-82 | Happ 8-6 | Peters 0-2 | Reyes 29 | 12,662 | |
| Sáb., 28 de Ago. | P13-0 | 47-83 | Wainwright 13-7 | Brault 0-3 | 20,043 | ||
| Dom., 29 de Ago. | G4-3 | 48-83 | Stratton 5-0 | Reyes 5-7 | 10,290 | ||
| Mar., 31 de Ago. | P4-2 | 48-84 | Kopech 4-2 | Wilson 2-6 | Hendriks 30 | 19,221 | |
| Mié., 1 de Sep. | P6-3 | 48-85 | Rodon 11-5 | Kranick 1-3 | Hendriks 31 | 19,231 | |
| Jue., 2 de Sep. | P6-5 F/11 | 48-86 | Heuer 6-2 | Howard 2-3 | 26,963 | ||
| Vie., 3 de Sep. | P6-5 | 48-87 | Megill 1-0 | Miller 0-1 | Wick 2 | 24,441 | |
| Sáb., 4 de Sep. | P7-6 | 48-88 | Effross 1-0 | Stratton 5-1 | 30,020 | ||
| Dom., 5 de Sep. | P11-8 | 48-89 | Alzolay 5-13 | Howard 2-4 | Wick 3 | 30,155 | |
| Lun., 6 de Sep. | G6-3 | 49-89 | Shreve 3-1 | Funkhouser 6-3 | Bednar 3 | 11,141 | |
| Mar., 7 de Sep. | G3-2 | 50-89 | Howard 3-4 | Lange 0-2 | Stratton 3 | 8,329 | |
| Mié., 8 de Sep. | P5-1 | 50-90 | Hutchison 1-1 | Keller 4-11 | 8,382 | ||
| Vie., 10 de Sep. | G4-3 | 51-90 | Kuhl 5-6 | Murphy 0-2 | 11,808 | ||
| Sáb., 11 de Sep. | G10-7 | 52-90 | Keller 1-1 | Baldonado 0-1 | Stratton 4 | 17,993 | |
| Dom., 12 de Sep. | P6-2 | 52-91 | Corbin 8-14 | Wilson 2-7 | Finnegan 9 | 9,714 | |
| Mar., 14 de Sep. | G6-5 | 53-91 | Peters 1-2 | Miley 12-6 | Stratton 5 | 8,896 | |
| Mié., 15 de Sep. | G5-4 | 54-91 | Stratton 6-1 | Givens 3-3 | 9,320 | ||
| Jue., 16 de Sep. | P1-0 | 54-92 | Mahle 12-5 | Ponce 0-4 | Givens 8 | 9,102 | |
| Vie., 17 de Sep. | G2-1 | 55-92 | Crowe 4-7 | Hernandez 1-2 | Stratton 6 | 7,884 | |
| Sáb., 18 de Sep. | G6-3 | 56-92 | Wilson 3-7 | Cabrera 0-2 | 12,300 | ||
| Dom., 19 de Sep. | P6-5 F/10 | 56-93 | Okert 2-1 | Kuhl 5-7 | 9,870 | ||
| Lun., 20 de Sep. | P9-5 | 56-94 | Cessa 5-2 | Ponce 0-5 | 17,086 | ||
| Mar., 21 de Sep. | G6-2 | 57-94 | Keller 5-11 | Mahle 12-6 | 9,475 | ||
| Mié., 22 de Sep. | Pospuesto | ||||||
| Jue., 23 de Sep. | P12-6 | 57-95 | Nola 9-8 | Banda 2-2 | 16,154 | ||
| Vie., 24 de Sep. | P8-6 | 57-96 | Neris 4-6 | Shreve 3-2 | Kennedy 26 | 20,548 | |
| FECHA | OPONENTE | HORA | TV | PITCHER | OP | tickets | |
| Sáb., 25 de Sep. | 4:05 PM | Crowe | Suarez | ||||
| Dom., 26 de Sep. | 1:05 PM | Kranick | |||||
| Lun., 27 de Sep. | 1:10 PM | Peters | Miley | ||||
| Mar., 28 de Sep. | 6:35 PM | Keller | Mills | ||||
| Mié., 29 de Sep. | 6:35 PM | Overton | Hendricks | ||||
| Jue., 30 de Sep. | 6:35 PM | Crowe | Davies | ||||
| Vie., 1 de Oct. | 6:35 PM | Kranick | Gutierrez | ||||
| Sáb., 2 de Oct. | 6:35 PM | Peters | Mahle | ||||
| Dom., 3 de Oct. | 3:05 PM | Keller | Miley | ||||
